CLINICAL CHARACTERIZATIONS AND MOLECULAR GENETIC STUDY OF TWO CO-SEGREGATING VARIANTS IN PDZD7 AND PDE6C GENES LEADING SIMULTANEOUSLY TO NON-SYNDROMIC HEARING LOSS AND ACHROMATOPSIA

Abstract Background Autosomal recessive non-syndromic hearing loss (NSHL) and cone dystrophies (CODs) are highly genetically and phenotypically heterogeneous disorders.In this study, we applied the whole exome sequencing (WES) to find the cause of HL and COD in an Iranian consanguineous family with three affected individuals.Methods Three members f

Synthetic aperture radar (SAR) ship detection has been playing an increasingly essential role in marine monitoring in recent years.The lack of detailed information about ships in wide swath SAR imagery poses difficulty for traditional methods in exploring effective features for ship discrimination.Being capable of feature representation, deep neura

Microcontrollers are programmable, integrated circuit chips.In the last two decades, their applications to industrial instruments, vehicles, and household appliances have reached the extent that microcontrollers are now the number-one selling electronic Baby Gift Set chip of all kinds.Simultaneously, the field of lab-on-a-chip research and technolo

We analyse the full counting statistics (FCS) of photons flowing in and out of a microwave cavity coupled to a voltage-biased Josephson junction.Tunnelling of Cooper pairs generates a coherent flow of photons into the cavity whilst at the same time photons can also leak out incoherently.We use a very general unitary transformation Module Controller